Serum asprosin levels in patients with retinopathy of prematurity

Abstract Objectives This study was aimed to investigate the diagnostic values of serum levels asprosin and neutrophil gelatinase-associated lipocalin (NGAL) in Retinopathy prematurity (ROP) assess role these biomarkers on development progression condition. Methods carried out from April 2020 February 2021 department ophthalmology a tertiary hospital Turkey. Thirty patients diagnosed with ROP 30 healthy newborns were included study. Serum NGAL determined via ELISA. Results The median found be similar between group control (p=0.595). Median significantly higher [46.58 (12.70–142.28) ng/mL] compared subjects [13.05 (10.92–17.73) (p=0.001). optimal cut-off value by ROC analysis ng/mL (AUC: 0.754, p=0.001) for diagnosing ROP. positively correlated ALP inversely gestational week, uric acid AST (all, p<0.005). Conclusions Our results demonstrated that asprosin, but not NGAL, could biomarker diagnosis